Just Gaze and Wave: Exploring the Use of Gaze and Gestures for Shoulder-surfing Resilient Authentication

Eye-gaze and mid-air gestures are promising for resisting various types of side-channel attacks during authentication. However, to date, a comparison of the different authentication modalities is missing. We investigate multiple authentication mechanisms that leverage gestures, eye gaze, and a multimodal combination of them and study their resilience to shoulder surfing. To this end, we report on our implementation of three schemes and results from usability and security evaluations where we also experimented with fixed and randomized layouts. We found that the gaze-based approach outperforms the other schemes in terms of input time, error rate, perceived workload, and resistance to observation attacks, and that randomizing the layout does not improve observation resistance enough to warrant the reduced usability. Our work further underlines the significance of replicating previous eye tracking studies using today's sensors as we show significant improvement over similar previously introduced gaze-based authentication systems

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Not AvailableBiopesticides are considered to be safe, target specific, biodegradable and eco-friendly. These, especially Azadirachta indica A. Juss. (neem) based biopesticides, are mainly used as emulsified concentrate (EC). There is growing interest in nano emulsions based on phytochemical mixtures due to their better efficacy compared to conventional biopesticides. A. indica seed oil and Cymbopogon nardus (L.) Rendle (Citronella) oil are known to have pest control properties. However, their utilization is often restricted due to relatively low water solubility. This drawback can be overcome by encapsulating oils in oil-in-water (O/W) emulsions or nano emulsions using low or high energy methods. In this study, various nano emulsions of crude neem and citronella oils with surfactants were developed and characterised by Dynamic Light Scattering (DLS) and Transmission Electron Microscope (TEM). Composition of various ingredients of nano emulsions was standardised. TEM study showed the spherical shape of neem and citronella oil nano emulsions. The average size of droplets of neem nano emulsion (NNE) with different percentage of citronella oil ranged from 11.23 ± 3.86 nm to 17.80 ± 4.52 nm while that of citronella nano emulsion (CNE) with different percentage of neem oil ranged from 8.12 ± 2.80 nm to 12.04 ± 3.74 nm. It was found that increase in surfactant ratio to neem oil or citronella oil decreases the size of droplets in nano emulsions. Further, in vitro antifungal study of against Rhizoctonia solani and Sclerotium rolfsii was carried out by poisoned food technique. Results showed that neem nano emulsion 10 (NNE10) and citronella nano emulsion 10 (CNE10) were most active against R. solani (ED50 13.67 mg L−1 and 25.64 mg L−1) and S. rolfsii (ED50 14.71 mg L−1 and 20.88 mg L−1). The standardization of the composition and development of citronella essential oil and neem oil based nano emulsions and their antifungal activity against these two fungi has been reported for the first time.Not Availabl

Efficacy of Tocilizumab in Management of COVID-19 Patients Admitted to Intensive Care Units: A Multicenter Retrospective Cohort Study

Background and Objectives: Mortality and illness due to COVID-19 have been linked to a condition known as cytokine release syndrome (CRS) that is characterized by excessive production of inflammatory cytokines, particularly interleukin-6 (IL-6). Tocilizumab (TCZ), a recent IL-6 antagonist, has been redeployed as adjunctive treatment for CRS remission in COVID-19 patients. This study aimed to determine the efficacy of Tocilizumab on patients’ survival and the length of stay in hospitalized COVID-19 patients admitted to the intensive care unit. Methods: Between January 2021 and June 2021, a multicenter retrospective cohort study was carried out in six tertiary care hospitals in Egypt’s governorate of Giza. Based on the use of TCZ during ICU stay, eligible patients were divided into two groups (control vs. TCZ). In-hospital mortality was the main outcome. Results: A total of 740 patient data records were included in the analysis, where 630 patients followed the routine COVID-19 protocol, while 110 patients received TCZ, need to different respiratory support after hospitalization, and inflammatory mediators such as C-reactive protein (CRP), ferritin, and Lactate dehydrogenase (LDH) showed a statistically significant difference between the TCZ group and the control group. Regarding the primary outcome (discharged alive or death) and neither the secondary outcome (length of hospital stay), there is no statistically significant difference between patients treated with TCZ and the control group. Conclusions: Our cohort of patients with moderate to severe COVID-19 did not assert a reduction in the risk of mortality or the length of stay (LOS) after TCZ administration